Grease two 9 × 5-inch loaf pans.
Make the filling. In a small bowl, stir together the crème fraîche, 1 tablespoon of the honey, the vanilla, lemon zest, lemon juice, and cinnamon.
Make the rolls. Turn out the dough onto a lightly floured work surface, punch it down, and roll it into a 10 × 16-inch rectangle about ½ inch thick, with a long side facing you. Spread the crème fraiche mixture over the dough and sprinkle the blueberries evenly on top. Starting with the long edge closest to you, pull the dough up and over the filling and carefully roll it into a log, keeping it fairly tight. Pinch the edge to seal.
Turn the log seam side down and cut it into 12 equal rolls. Place 6 rolls, seam side down, in each prepared pan; the rolls should touch. Cover and let rise in a warm place until almost doubled in size, 30 minutes to 1 hour.
Preheat the oven to 350°F.
Bake the rolls until lightly browned on top, 45 to 50 minutes. Set aside to cool slightly.
Make the thyme honey. Meanwhile, combine the thyme and the remaining ¼ cup of honey in a small saucepan over low heat. Simmer until the honey begins to bubble, about 3 minutes, and remove the pan from the heat.
Drizzle the bread with the warm thyme honey. Store any leftovers refrigerated in an airtight container for up to 3 days. This recipe makes enough for two loaves of bread. Bake them both, or freeze one for later. To freeze, wrap the baked bread in plastic wrap and freeze for up to 3 months. Thaw overnight on the counter, add the thyme honey, and enjoy!